N-glycolylneuraminic acid as a carbohydrate cancer biomarker

J Wang, LK Shewell, CJ Day, MP Jennings - Translational Oncology, 2023 - Elsevier
… b 5 reductase, and Fe 2+ ions for its enzymatic activity. … Cmah −/− mice (the MMTV-PyMT
transgenic mouse is a model … surface of erythrocytes in cats determines their blood serotypes: …

[HTML][HTML] Synthesis of N-glycolylneuraminic acid (Neu5Gc) and its glycosides

AS Kooner, H Yu, X Chen - Frontiers in immunology, 2019 - frontiersin.org
… in the cytosol from CMP-Neu5Ac by CMP-Neu5Ac hydroxylase (… in protecting mice from
endotoxemia by inhibiting mouse … chromatography and gel filtration column purification (88). …

From “serum sickness” to “xenosialitis”: Past, present, and future significance of the non-human sialic acid Neu5Gc

C Dhar, A Sasmal, A Varki - Frontiers in immunology, 2019 - frontiersin.org
… N-acetylneuraminic acid hydroxylase (Cmah) (9–13). The … as inhibition of bovine erythrocyte
agglutination by human HD … , which we use to immunize Cmah null mice against Neu5Gc-…

Loss of Neu5Gc during Human Evolution: Impact on Macrophage Inflammation and Muscle Metabolism

J Okerblom - 2017 - escholarship.org
… Macrophages and whole blood from Cmah-/- mice also killed … reported that CMAH was the
hydroxylase/mono-oxygenase … co-factors, including cytochrome b5/b5 reductase, iron, oxygen…

Intramolecular lactones of sialic acids

P Rota, P La Rocca, P Allevi, C Pappone… - International Journal of …, 2020 - mdpi.com
… of mouse embryonic tissues nor in the newborn or the adult … were absent from the red blood
cell (RBC) samples of healthy … biological samples using multi-step extraction and purification

The effect of glucose depletion and media supplementation on the productivity and quality of monoclonal antibodies production

C Villacrés - 2018 - mspace.lib.umanitoba.ca
… In addition, CMPN-acetylneuraminic acid act as a donor for sialylation of glycoproteins.
CMP-Sia is the only monosaccharide which activation occurs as a mononucleotide in the …